Separation of Enantiomers
In one handy volume this handbook summarizes the most common synthetic methods for the separation of racemic mixtures, allowing an easy comparison of the different strategies described in the literature. Alongside classical methods, the authors also consider kinetic resolutions, dynamic kinetic resolutions, divergent reactions of a racemic mixture, and a number of 'neglected' cases not covered elsewhere, such as the use of circularly polarized light, polymerizations, 'ripening' processes, dynamic combinatorial chemistry, and several thermodynamic processes. The result is a thorough introduction to the field plus a long-needed, up-to-date overview of the chemical, biological, and physical methods and their applications. Newcomers to the field, students as well as experienced synthetic chemists will benefit from the highly didactic presentation: Every method is presented in detail, from relatively simple separation problems to advanced complex resolution methods. A senior lecturer at the University of Sydney's School of Chemistry, Matthew Todd gained his BA and PhD from Cambridge University, UK, where he later became a fellow in chemistry. Prior to taking up his current position in 2006, he was a postdoctoral fellow at the University of California, Berkeley, USA, from 1999 to 2000, and then became a lecturer in organic chemistry at the Department of Chemistry, Queen Mary, University of London from 2001 to 2005. Dr. Todd has received several grants as well as the Accelerating Science Award Program in recognition of his open source malaria project. He has participated in 8 conferences, and has 45 journal articles and a book chapter to his name. Alongside open source drug discovery, his research group is investigating synthetic methodology, responsive metal complexes, and asymmetric catalysis.
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